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Emergency and basal feedback loops regulating myelopoiesis

Emergency and basal feedback loops regulating myelopoiesis
Feedback loops regulate myelopoiesis during the acute response to infection and in the steady state. Refer to UpToDate topics on myelopoieisis for further details.
HSC: hematopoieitic stem cell; CMP: common myeloid progenitor cell; CFU-GM: colony forming unit, granulocyte/macrophage; CFU-M: colony forming unit, macrophage; CFU-G: colony forming unit, granulocyte; T-reg: regulatory T cell; G-CSF: granulocyte colony-stimulating factor; C-CSFR: granulocyte colony-stimulating factor receptor; TLR4: toll-like receptor 4.
Based on a figure created by Colin A Sieff, MB, BCh, FRCPath.
Graphic 97523 Version 1.0