High power histology of a well-differentiated hepatocellular carcinoma
High power histology of a well-differentiated hepatocellular carcinoma
(A) Well-differentiated hepatocellular carcinoma, which is composed of tumor cells with mild atypia, a higher nuclear to cytoplasmic ratio than seen in normal hepatocytes, and rare pseudoglandular structures (arrows). (B) At higher power, the tumor is composed of polygonal tumor cells with eosinophilic cytoplasm, arranged in trabeculae that are more than two cells thick.