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Differential diagnosis of skin-colored papules, nodules, and plaques on the vulva

Differential diagnosis of skin-colored papules, nodules, and plaques on the vulva
Common Less common Rare
  • Vulvar papillomatosis
  • Skin tags (acrochordons)
  • Squamous intraepithelial lesions:
    • Low-grade squamous intraepithelial lesions
    • High-grade squamous intraepithelial lesions
    • Differentiated vulvar intraepithelial neoplasia 
  • Lichen simplex chronicus
  • Scar 
  • Epidermoid cyst
  • Molluscum contagiosum
  • Bartholin duct cyst
  • Intradermal melanocytic nevus 
  • Squamous cell carcinoma
  • Vestibular mucinous cyst 
  • Basal cell carcinoma
  • Hidradenoma papilliferum
  • Syringomas
  • Fox-Fordyce disease
  • Neurofibroma
  • Condylomata lata
The prevalence categories refer to vulvar manifestations of the listed diseases. The relative frequency of each may vary based on the patient population, geography, and type of clinical practice (eg, gynecology, dermatology, or internal medicine). While the above lesions may present as skin colored, they may also present with other colors. For some, skin-colored presentations may be less common.
Graphic 95996 Version 8.0

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