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Staging of acute kidney injury in children: Kidney Disease Improving Global Outcomes (KDIGO) criteria

Staging of acute kidney injury in children: Kidney Disease Improving Global Outcomes (KDIGO) criteria
Stage SCr Urine output
1 Increase to 1.5 to 1.9 times baseline, or increase of ≥0.3 mg/dL (≥26.5 mcmol/L) <0.5 mL/kg per hour for 6 to 12 hours
2 Increase to 2 to 2.9 times baseline <0.5 mL/kg per hour for ≥12 hours
3

Increase greater than 3 times baseline, or

SCr ≥4 mg/dL (≥353.6 mcmol/L), or

Initiation of kidney replacement therapy, or

eGFR <35 mL/min per 1.73 m2 (<18 years)

<0.3 mL/kg per hour for ≥24 hours, or

Anuria for ≥12 hours
The time frames for the increases in SCr are:
  • Increase of SCr ≥0.3 mg/dL (≥26.5 mcmol/L) within 48 hours
  • Increase in SCr >1.5 times the baseline within the prior 7 days
eGFR: estimated glomerular filtration rate; SCr: serum creatinine.
Reprinted by permission from Macmillan Publishers Ltd: Kidney International Supplements. Summary of Recommendation Statements. Kidney Disease: Improving Global Outcomes (KDIGO) Acute Kidney Injury Work Group. KDIGO Clinical Practice Guideline for Acute Kidney Injury. Kidney Int Suppl 2012; 2:8. Copyright © 2012. www.nature.com/kisup.
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