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Risk factors for pulmonary arterial hypertension in patients with systemic sclerosis

Risk factors for pulmonary arterial hypertension in patients with systemic sclerosis
Long standing disease (>5 years)
Limited cutaneous disease
Telangiectasia
DLCO <60 percent predicted
FVC percent/DLCO percent >1.6
Anti-centromere antibody
Anti-nucleolar pattern ANA
Anti-U1 RNP antibody
Absence of anti-Scl 70 antibody
Older age at onset of scleroderma
Elevated N-terminal pro BNP
DLCO: diffusion capacity for carbon monoxide; FVC: forced vital capacity; RNP: ribonuclear protein; BNP: brain natriuretic peptide.
Graphic 93544 Version 2.0

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