Rotavirus vaccines

(A) Attenuated human rotavirus vaccine (RV1, HRV) is a monovalent vaccine derived from the most common human rotavirus serotype combination (G1P[8]) that has been attenuated by serial passage in cell culture.
(B) Pentavalent human-bovine rotavirus reassortant vaccine (RV5, PRV) is a reassortant vaccine that combines the bovine strain, WC3, and a single gene encoding an outer capsid protein (VP7 or VP4) from the most common human serotypes: G1, G2, G3, G4, and P[8].