Brand Names: US
- Artificial Tears [OTC] [DSC];
- Biolle Gel Tears [OTC];
- Biolle Tears [OTC];
- Eyes Alive [OTC];
- FT Lubricant Eye Drops [OTC];
- GoodSense Lubricating Plus PF [OTC];
- Lubricant Eye Drops PF [OTC];
- Lubricant Eye Drops [OTC];
- Lubricating Plus Eye Drops [OTC] [DSC];
- Lubricating Tears Eye Drops [OTC];
- Refresh Celluvisc [OTC];
- Refresh Digital PF [OTC];
- Refresh Digital [OTC];
- Refresh Liquigel [OTC];
- Refresh Optive Advanced PF [OTC];
- Refresh Optive Advanced [OTC];
- Refresh Optive Mega-3 [OTC];
- Refresh Optive PF [OTC];
- Refresh Optive [OTC];
- Refresh Plus [OTC];
- Refresh Relieva PF [OTC];
- Refresh Relieva [OTC];
- Refresh Tears PF [OTC];
- Refresh Tears [OTC];
- Retaine CMC [OTC];
- Sterile Lubricant [OTC];
- TheraTears Extra PF [OTC];
- TheraTears Extra [OTC];
- TheraTears Nighttime [OTC];
- Theratears PF [OTC];
- Theratears [OTC];
- Ultra Fresh [OTC];
- Ventiva Tears Plus [OTC] [DSC];
- Ventiva Tears [OTC] [DSC]
Pharmacologic Category
-
Ophthalmic Agent, Miscellaneous
Dosing: Adult
Dry eyes
Dry eyes: Ophthalmic: Instill 1-2 drops into eye(s) 3-4 times/day
Dosing: Older Adult
Refer to adult dosing.
Adverse Reactions
There are no adverse reactions listed in the manufacturer's labeling.
Dosage Forms: US
Excipient information presented when available (limited, particularly for generics); consult specific product labeling. [DSC] = Discontinued product
Gel, Ophthalmic, as sodium:
Refresh Liquigel: 1% (15 mL)
Refresh Optive: 1 % (10 mL)
Theratears: 1% (28 ea [DSC]) [contains calcium chloride anhydrous, magnesium chloride, potassium chloride, sodium bicarbonate, sodium chloride, sodium phosphate]
Gel, Ophthalmic, as sodium [preservative free]:
Biolle Gel Tears: 1% (1 ea)
Refresh Celluvisc: 1% (30 ea)
TheraTears Nighttime: 1% (30 ea)
Liquid, Ophthalmic, as sodium:
Sterile Lubricant: 0.7% (15 mL)
Solution, Ophthalmic [preservative free]:
Ventiva Tears Plus: 0.6% (15 mL [DSC])
Solution, Ophthalmic, as sodium:
Artificial Tears: 1% (15 mL [DSC])
FT Lubricant Eye Drops: 0.5% (30 ea)
GoodSense Lubricating Plus PF: 0.5% (30 ea)
Lubricant Eye Drops: 0.5% (15 mL)
Lubricating Plus Eye Drops: 0.5% (30 ea [DSC], 50 ea [DSC])
Lubricating Tears Eye Drops: 0.5% (15 mL)
Refresh Digital: 0.5% (10 mL)
Refresh Liquigel: 1% (30 mL)
Refresh Optive: 0.5% (15 mL)
Refresh Optive Advanced: 0.5% (10 mL)
Refresh Plus: 0.5% (30 ea, 50 ea, 70 ea)
Refresh Relieva: 0.5% (10 mL)
Refresh Tears: 0.5% (15 mL, 30 mL)
Retaine CMC: 0.5% (30 ea)
Theratears: 0.25% (15 mL, 30 mL) [contains calcium chloride, magnesium chloride, potassium chloride, sodium bicarbonate, sodium chloride, sodium phosphate, monobasic monohydrate]
TheraTears Extra: 0.25% (15 mL)
Ultra Fresh: 0.5% (15 mL, 30 mL)
Generic: 0.5% (15 mL)
Solution, Ophthalmic, as sodium [preservative free]:
Biolle Tears: 0.5% (32 ea)
Eyes Alive: 0.5% (32 ea)
Lubricant Eye Drops PF: 0.5% (30 ea, 50 ea)
Refresh Digital PF: 0.5% (30 ea)
Refresh Optive Advanced PF: 0.5% (30 ea)
Refresh Optive Mega-3: 0.5% (60 ea) [nacl free]
Refresh Optive Mega-3: 0.5% (30 ea)
Refresh Optive PF: 0.5% (30 ea, 60 ea)
Refresh Plus: 0.5% (30 ea, 50 ea)
Refresh Relieva PF: 0.5% (30 ea, 10 mL)
Refresh Tears PF: 0.5% (10 mL)
TheraTears Extra PF: 0.25% (30 ea)
Theratears PF: 0.25% (30 ea)
Ventiva Tears: 0.5% (15 mL [DSC])
Generic: 0.5% (30 ea)
Generic Equivalent Available: US
May be product dependent
Pricing: US
Gel (Biolle Gel Tears Ophthalmic)
1% (per each): $0.30
Gel (Refresh Celluvisc Ophthalmic)
1% (per each): $0.44
Gel (Refresh Liquigel Ophthalmic)
1% (per mL): $0.69
Gel (Refresh Optive Ophthalmic)
1-0.9% (per mL): $1.32
Gel (TheraTears Nighttime Ophthalmic)
1% (per each): $0.52
Liquid (Sterile Lubricant Ophthalmic)
0.7% (per mL): $0.41
Solution (Biolle Tears Ophthalmic)
0.5% (per each): $0.30
Solution (Carboxymethylcellulose Sod PF Ophthalmic)
0.5% (per each): $0.81
Solution (Carboxymethylcellulose Sodium Ophthalmic)
0.5% (per mL): $0.40 - $0.73
Solution (Eyes Alive Ophthalmic)
0.5% (per each): $0.30
Solution (Refresh Digital Ophthalmic)
0.5-1-0.5% (per mL): $1.24
Solution (Refresh Digital PF Ophthalmic)
0.5-1-0.5% (per each): $0.47
Solution (Refresh Optive Advanced Ophthalmic)
0.5-1-0.5% (per mL): $0.97
Solution (Refresh Optive Advanced PF Ophthalmic)
0.5-1-0.5% (per each): $0.48
Solution (Refresh Optive Mega-3 Ophthalmic)
0.5-1-0.5% (per each): $0.54
Solution (Refresh Optive Ophthalmic)
0.5-0.9% (per mL): $0.79
Solution (Refresh Optive PF Ophthalmic)
0.5-0.9% (per each): $0.41
Solution (Refresh Plus Ophthalmic)
0.5% (per each): $0.33
Solution (Refresh Relieva Ophthalmic)
0.5-0.9% (per mL): $1.31
Solution (Refresh Relieva PF Ophthalmic)
0.5-0.9% (per mL): $1.51
0.5-1% (per each): $0.54
Solution (Refresh Tears Ophthalmic)
0.5% (per mL): $0.49
Solution (Refresh Tears PF Ophthalmic)
0.5-0.9% (per mL): $1.20
Solution (Retaine CMC Ophthalmic)
0.5% (per each): $0.40
Solution (TheraTears Extra Ophthalmic)
0.25% (per mL): $0.76
Solution (TheraTears Extra PF Ophthalmic)
0.25% (per each): $0.62
Solution (Theratears Ophthalmic)
0.25% (per mL): $0.93
Solution (Theratears PF Ophthalmic)
0.25% (per each): $0.52
Solution (Ultra Fresh Ophthalmic)
0.5% (per mL): $0.56
Disclaimer: A representative AWP (Average Wholesale Price) price or price range is provided as reference price only. A range is provided when more than one manufacturer's AWP price is available and uses the low and high price reported by the manufacturers to determine the range. The pricing data should be used for benchmarking purposes only, and as such should not be used alone to set or adjudicate any prices for reimbursement or purchasing functions or considered to be an exact price for a single product and/or manufacturer. Medi-Span expressly disclaims all warranties of any kind or nature, whether express or implied, and assumes no liability with respect to accuracy of price or price range data published in its solutions. In no event shall Medi-Span be liable for special, indirect, incidental, or consequential damages arising from use of price or price range data. Pricing data is updated monthly.
Use: Labeled Indications
Artificial tear substitute
Medication Safety Issues
Sound-alike/look-alike issues:
Refresh Celluvisc may be confused with Restasis
Metabolism/Transport Effects
None known.
Drug Interactions
There are no known significant interactions.
Brand Names: International
International Brand Names by CountryFor country code abbreviations (
show table)
-
(AE) United Arab Emirates: Refresh | Refresh Contact | Refresh tears;
-
(AR) Argentina: Aliviamax | Aqua lent lubricante | Aucic | Aucic lc | Natura fresh | Refresh | Refresh tears;
-
(AU) Australia: Evolve Carmellose | Optifresh plus | Refresh;
-
(BD) Bangladesh: Aquafresh | Cfresh liquigel | Dewgel | Drylief | Freshfil | Lacrigel | Lubgel | Lubrimax | Refresh liquigel | Retears | Sinafresh | Tearfresh liquigel | Tearon fresh | Tr care;
-
(BR) Brazil: Acu fresh | Adaptis | Dews | Ecofilm | Fresh tears | Fresh tears liquigel | Lacrifilm | Lacrilax | Liris | Neo fresh | Plenigell;
-
(CH) Switzerland: Cellufluid | Celluvisc;
-
(CL) Chile: Carmelosa sodica | Freegen | Liris | Refresh | Refresh tears;
-
(CN) China: Celluvisc | Refresh celluvisc | Refresh plus;
-
(CO) Colombia: Acuxim | Carboximetilcelulosa sodica | Carmelub tears | Carmelub tearsgel | Carsof | Disofresh | Expofresh | Fergest | Freegen | Freegen pf | Labsoft | Lagrigen | Lagrigen procaps | Lagrikov | Lagrimart | Lubrioph | Oftalmotrilub | Oftipres | Oftitears | Oq tears | Refresh | Refresh liquigel | Refresh tears | Tearsoft | Thera tears | Vital vision;
-
(DO) Dominican Republic: Cristaltears | Lubrifres | Nass | Refresh | Refresh tears | Refreskan T;
-
(EC) Ecuador: Carboximetilcelulosa sodica | Carmelub | Cristal Tears | Cristaltears | Refresh | Refresh liquigel | Refresh tears | Tearsoft;
-
(EE) Estonia: Oftalong;
-
(EG) Egypt: Celluvisc | Lacritears | Pharma tears | Refresh | Refresh tears;
-
(ES) Spain: Optava;
-
(ET) Ethiopia: Aqualube;
-
(GB) United Kingdom: Aqualube | Aqualube forte | Carmellose | Carmize | Cellusan | Cellusan light | Evolve Carmellose | I dew ds | Lumecare evolve | Optho lique | Optho lique forte | Pf drops carmellose sodium | Tearvis | Theratears;
-
(HK) Hong Kong: Refresh | Refresh tears;
-
(IE) Ireland: Pf drops carmellose sodium;
-
(IL) Israel: Refresh tears;
-
(IN) India: Add tears | Aftee | Aqualube | Aquaray | Aquaray gel | Aquasurge | Arotear | Asrugen | C | Care tears | Carmace m | Carmet | Ccs | Cellomist | Celumac | Ckes | Cmc | Compu | Cornifresh | Eco tears | Eluba | Enlube | Eryxolub | Extralube | Eyelet | Eyemac | Eyemac gb | Eyequa | Eyespa | Flogel | Frenix | Freshika h tears | Fresview | Gembloc | Glacial | Glytears | Hy5 plus | Ilife | Ionosight | Irivisc | Irivisc Liquigel | Just Tears | K fresh | Lacrimos | Loctears | Locula tr | Lubistar cmc | Lubrex | Lubrex uno | Lubrifresh | Magmoist | Misty | Moss Plus | No dry | Notear | OnTears | Ontears mini | Optimoist | Optimoist ds | Optiview | Osmo tear | Oxilube | Pearl tears | Pixelub multi | Pseudo tears | Re lub | Refresh | Refresh tears | Rejuvtears | Relub ds | Relub lc | Richgel Tears | Smartears | Softvisc | Solufresh | Super Tears | Takfresh | Takfresh gel | Tear | Tear safe | Tearlub | Tearmax | Tearsgel | Ultragel | Veldrop | Viter | Wat r | Wetica | Wetye | Zonafresh | Zyaqua;
-
(IT) Italy: Carbossimetilcell | Carbossimetilcellu;
-
(JO) Jordan: Alifresh tears | Refresh;
-
(KE) Kenya: Komfort xtra | Loc tears | Tear | Veldrop;
-
(KR) Korea, Republic of: Aufresh | Bearfresh | Hanlim cmc | Hyai eye fresh | I mc | Il yang 2i | Infresh f | Max relief | Maxclear | Refresh | Refresh tears;
-
(KW) Kuwait: Celluvisc | Refresh | Refresh tears;
-
(LB) Lebanon: Celluvisc | Hydradrop | Refresh tears;
-
(LT) Lithuania: Ekg;
-
(LV) Latvia: Ekg;
-
(MX) Mexico: Lubrex | Refresh | Refresh Contacts | Refresh tears | Refresh-tears | Tear cmc;
-
(MY) Malaysia: Clarastill | I dew ds | Loc tears fusion | Refresh | Refresh liquigel | Refresh tears;
-
(NG) Nigeria: Maxi tears;
-
(NZ) New Zealand: Biomed Carboxymethyl;
-
(PE) Peru: Akw agelak | Akwagel free | Celluvisc | Cristaltears | Freegen | Fresh tears | Lagrifresh | Lubriyet | Ocutears free | Refresh | Refresh tears | Refreskan T;
-
(PH) Philippines: Cellufresh | Cellufresh md | Celluvisc md | Clarastill | Eyelube | Just Tears;
-
(PK) Pakistan: Optheez | Recuro;
-
(PR) Puerto Rico: Lubricating plus | Refresh | Refresh liquigel | Thera tears | Thera tears extra | Theratears;
-
(PT) Portugal: Inoclear | Refresh tears;
-
(PY) Paraguay: Aucic;
-
(QA) Qatar: Optive | Refresh Plus;
-
(SA) Saudi Arabia: Refresh | Refresh plus | Refresh tears;
-
(SG) Singapore: Refresh | Refresh Contacts | Refresh tears;
-
(SL) Sierra Leone: Tear klic;
-
(TH) Thailand: Cellufresh | Celluvisc | Intrasite | Tear mac;
-
(TR) Turkey: Refresh liquigel | Refresh tears;
-
(TW) Taiwan: Refresh | Refresh celluvisc | Refresh tear;
-
(UG) Uganda: Carbosol | Fresh eyes | Lubrex | Tearlin | Tearmax;
-
(UY) Uruguay: Akw agelak | Cristaltears | Lacrimax | Refresh tears;
-
(VE) Venezuela, Bolivarian Republic of: Clarifresh | Clean tear | Lagrifresh | Lagrimart | Refresh | Refresh tears | Tearsoft;
-
(ZA) South Africa: Dri gon | I dew | Loc tears fusion | Refresh tears;
-
(ZM) Zambia: Veldrop