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Benzoin: Drug information

Benzoin: Drug information
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For additional information see "Benzoin: Patient drug information" and "Benzoin: Pediatric drug information"

For abbreviations, symbols, and age group definitions show table
Brand Names: US
  • Benz-Protect [OTC] [DSC];
  • SprayZoin [OTC] [DSC]
Pharmacologic Category
  • Antiseptic, Topical;
  • Topical Skin Product
Dosing: Adult
Adhesive

Adhesive: Topical: Apply a thin film to skin on each side of the wound.

Mouth/skin protectant

Mouth/skin protectant: Topical:

Spray: Apply 2 to 3 times daily or as directed.

Swabs: Apply every 3 to 4 hours or as directed.

Tincture: Apply not more than every 2 hours.

Dosing: Kidney Impairment: Adult

There are no dosage adjustments provided in the manufacturer's labeling.

Dosing: Hepatic Impairment: Adult

There are no dosage adjustments provided in the manufacturer's labeling.

Dosing: Older Adult

Refer to adult dosing.

Dosing: Pediatric

(For additional information see "Benzoin: Pediatric drug information")

Skin protectant

Skin protectant:

Liquid: First-aid treatment, antiseptic: Children and Adolescents: Apply to affected area

Spray: Children and Adolescents: Apply to affected area of skin 2 to 3 times daily or as directed

Swabs: Children ≥2 years and Adolescents: Apply to dry skin or oral mucosa (as applicable) every 3 to 4 hours or as directed

Dosing: Kidney Impairment: Pediatric

There are no dosage adjustments provided in the manufacturer's labeling.

Dosing: Hepatic Impairment: Pediatric

There are no dosage adjustments provided in the manufacturer's labeling.

Adverse Reactions

The following adverse drug reactions and incidences are derived from product labeling unless otherwise specified. Frequency not defined.

Dermatologic: Contact dermatitis (Sasseville 2009)

Warnings/Precautions

Other warnings/precautions:

• Self-medication (OTC use): Patients should be instructed to discontinue use and contact health care provider if rash, swelling, skin irritation, infection, or persistence of pain occurs. Consult health care provider for use >10 days.

Dosage Forms: US

Excipient information presented when available (limited, particularly for generics); consult specific product labeling. [DSC] = Discontinued product

Liquid, External:

SprayZoin: (120 mL [DSC])

Swab, External:

Benz-Protect: (1 ea [DSC])

Tincture, External:

Generic: (1 mL, 29 mL [DSC], 58 mL [DSC], 59 mL, 60 mL [DSC], 100 mL, 118 mL [DSC], 473 mL, 500 mL, 4000 mL, 20000 mL)

Generic Equivalent Available: US

May be product dependent

Administration: Adult

Topical: For external use only; not for ophthalmic use. Clean and dry affected area prior to use.

Adhesive: Gently squeeze vial to crush inner ampule. Allow liquid to saturate the tip of the vial. Apply thin film to the skin on each side of the wound. Allow liquid to dry ~30 to 40 seconds before applying bandages.

Mouth/skin protectant:

Spray: Shake well before use. Spray liberally to affected area or under adhesive tapes, casts, and orthopedic devices.

Swabs: Apply with swab applicator to affected area.

Tincture: Apply undiluted with cotton swab to canker sores. Do not swallow.

Administration: Pediatric

Topical: For external use only; not for ophthalmic use. Clean and dry skin prior to use.

Spray: Shake well before use. Spray liberally to affected area or under adhesive tapes, casts, and orthopedic devices.

Swabs: Dry the affected area of skin or oral mucosa; apply with swab applicator to affected area.

Use: Labeled Indications

Adhesive: Protective adhesive to hold bandages in place.

Mouth/skin protectant: Protective application for skin wounds or canker sores; protects skin under adhesive tapes, casts, and orthopedic devices.

Metabolism/Transport Effects

None known.

Drug Interactions

There are no known significant interactions.

  1. Benzoin spray [prescribing information]. Saint Louis, MO: Allied Healthcare; no date.
  2. Benzoin tincture (benzoin) [prescribing information]. Austin, TX: Humco; November 2017.
  3. Benz-Protect Swab (benzoin) [prescribing information]. Mount Vernon, NY: Geritrex Corporation; October 2017.
  4. Compound benzoin tincture [prescribing information]. Blairstown, NJ: James Alexander Corporation; April 2011.
  5. Sasseville D, Saber M, Lessard L. Allergic contact dermatitis from tincture of benzoin with multiple concomitant reactions. Contact Dermatitis. 2009;61(6):358-360. [PubMed 20059502]
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