Pathways involved in kinin-mediated angioedema and actions of drugs
Pathways involved in kinin-mediated angioedema and actions of drugs
C4: complement component 4; C1INH: C1 inhibitor. * In the disorder hereditary angioedema (HAE) with factor XII mutations, factor XII may be prone to excessive activation.
Data from:
Morgan PB. Hereditary angioedema—therapies old and new. N Engl J Med 2010; 363:581.
Longhurst H, Cicardi M. Hereditary angio-oedema. Lancet 2012; 379:474.