Nature of operation | Common pathogens | Recommended antimicrobials | Usual adult dose* | Redose interval¶ |
Arterial surgery involving a prosthesis, the abdominal aorta, or a groin incision | Staphylococcus aureus, S. epidermidis, enteric gram-negative bacilli | Cefazolin | <120 kg: 2 g IV ≥120 kg: 3 g IV | 4 hours |
OR vancomycinΔ | 15 mg/kg IV (max 2 g) | N/A | ||
OR clindamycin | 900 mg IV | 6 hours | ||
Lower extremity amputation for ischemia | S. aureus, S. epidermidis, enteric gram-negative bacilli, clostridia | Cefazolin | <120 kg: 2 g IV ≥120 kg: 3 g IV | 4 hours |
OR vancomycinΔ | 15 mg/kg IV (max 2 g) | N/A | ||
OR clindamycin | 900 mg IV | 6 hours |
Do you want to add Medilib to your home screen?