Nature of operation | Common pathogens | Recommended antimicrobials | Usual adult dose* | Redose interval¶ |
Thoracic (noncardiac) procedures: lobectomy, pneumonectomy, lung resection, thoracotomy | Staphylococcus aureus, Staphylococcus epidermidis, streptococci, enteric gram-negative bacilli | Cefazolin | <120 kg: 2 g IV ≥120 kg: 3 g IV | 4 hours |
OR ampicillin-sulbactamΔ | 3 g IV | 2 hours | ||
OR vancomycin◊ | 15 mg/kg IV (max 2 g) | N/A | ||
OR clindamycin | 900 mg IV | 6 hours |
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