Points | Age (years) | ECOG performance status | LDH:ULN ratio | WBC (109/L) |
0 | <50 | 0 to 1 | <0.67 | <6.7 |
1 | 50 to 59 | 0.67 to 0.99 | 6.7 to 9.9 | |
2 | 60 to 69 | 2 to 4 | 1.00 to 1.49 | 10.0 to 14.9 |
3 | ≥70 | ≥1.50 | ≥15.00 | |
One to three points is given for each of the above characteristics present in the patient with MCL, for a total score ranging from zero to 12. When applied to a study of long term survival in 455 patients with MCL diagnosed between 1996 and 2004, the following three risk groups and their corresponding median and five-year survivals were as follows: | ||||
Score | Risk group | Median survival | Five-year OS | |
0 to 3 points | Low risk | Not reached | 60 percent | |
4 to 5 points | Intermediate risk | 58 months | 35 percent | |
6 to 12 points | High risk | 37 months | 20 percent |
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