Potential complications of acute diarrheal disease in adults

Complication	Associated bacterial agent	Comments
Bacteremia	Shigella species, Nontyphoidal Salmonella enterica, Campylobacter fetus	Particular concern in HIV-infected individuals
Hemolytic-uremic syndrome	Shigella species, Shiga toxin-producing Escherichia coli	Shiga toxins are responsible for damage to endothelial cells and hemolytic-uremic syndrome
Guillain-Barré syndrome	Campylobacter jejuni
Reactive arthritis	Campylobacter species, Salmonella species, Shigella flexneri

Courtesy of Regina C LaRocque, MD, MPH, and Mark Pietroni, MA, FRCP, FFPH, DTM&H.

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