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Esophageal pressure topography plot of achalasia subtypes in the Chicago Classification

Esophageal pressure topography plot of achalasia subtypes in the Chicago Classification
In each case, the 30 mmHg isobaric contour is highlighted in black and there is impaired EGJ relaxation evident by the EGJ never relaxing to less than 30 mmHg in any panel. With type I achalasia, there is minimal contractile activity between the UES and EGJ. Type II is defined by ≥20 percent of swallows (supine posture, 5 mL water) with panesophageal pressurization to ≥30 mmHg. With type III, there is ≥20 percent of swallows with either premature contractions or fragments of peristalsis.
EGJ: esophagogastric junction; UES: upper esophageal sphincter.
Original figure modified for this publication. Pandolfino JE, Kwiatek MA, Nealis T, et al. Achalasia: a new clinically relevant classification by high-resolution manometry. Gastroenterology 2008; 135:1526. Illustration used with the permission of Elsevier Inc. All rights reserved.
Graphic 86439 Version 2.0

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