Hereditary MTC (germline RET mutation present) | 25% |
Sporadic MTC (no germline RET mutation identified) | 75% |
Sporadic MTC (no germline RET mutation identified) | |
• No somatic RET mutations found | 35% |
• Somatic RET mutations found | 65% |
- Exon 16, codon 918 | 60% |
- Exon 11, codon 630, 634 | 21% |
- Exon 10, codon 609, 620 | 9% |
- Exon 15, codon 891 | 9% |
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