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Version August 2025
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Urinary indices differentiating prerenal acute kidney injury from acute tubular necrosis (intrinsic acute kidney injury)
Urinary indices differentiating prerenal acute kidney injury from acute tubular necrosis (intrinsic acute kidney injury)
Measurement
Prerenal AKI
Intrinsic AKI
Urine specific gravity
>1.020
<1.010
Urine/plasma creatinine
>40
<20
Urine Na (mEq/L)
<20
>40
FENa
<1%
>2%
FEUrea
<35%
>50%
AKI: acute kidney injury; FENa: fractional excretion of sodium; FEUrea: fractional excretion of urea; Na: sodium.
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