A: Photograph of a surgically resected urinary bladder opened anteriorly to show urothelial carcinoma involving the mucosa that surrounds the orifices of the ureters. B: Cross-section of urinary bladder wall demonstrating transmural diffuse growth of urothelial carcinoma. The tumor invades the perivesical adipose tissue. C: Microscopic appearance of invasive urothelial carcinoma (20x).