Survival benefit of continuous long-term oxygen therapy in COPD
Survival benefit of continuous long-term oxygen therapy in COPD
The Nocturnal Oxygen Therapy Trial randomly assigned 203 patients with chronic obstructive pulmonary disease complicated by hypoxemia to treatment with nearly continuous oxygen therapy (red line) or nocturnal oxygen alone (blue line). Continuous oxygen therapy was associated with a significant survival benefit (p = 0.01).
Redrawn from Nocturnal Oxygen Trial Therapy Group, Ann Intern Med 1980; 93:391.