Organism | Antifungal agent | Number tested | MIC (mcg/mL) | |
50 percent* | 90 percent* | |||
Aspergillus fumigatus | Amphotericin B¶ | 1119 | 0.5 | 1 |
Itraconazole | 1119 | 0.5 | 1 | |
Isavuconazole | 855 | 0.5 | 1 | |
Posaconazole | 1119 | 0.12 | 0.5 | |
Voriconazole | 1119 | 0.25 | 0.5 | |
Caspofungin | 256 | 0.03 | 0.06 | |
Aspergillus flavus | Amphotericin B¶ | 89 | 1 | 2 |
Itraconazole | 89 | 0.5 | 1 | |
Isavuconazole | 444 | 0.5 | 1 | |
Posaconazole | 89 | 0.25 | 0.5 | |
Voriconazole | 89 | 0.5 | 1 | |
Caspofungin | 30 | 0.03 | 0.06 | |
Aspergillus niger | Amphotericin B¶ | 101 | 0.12 | 1 |
Itraconazole | 101 | 1 | 2 | |
Isavuconazole | 207 | 1 | 2 | |
Posaconazole | 101 | 0.25 | 0.5 | |
Voriconazole | 101 | 0.5 | 2 | |
Caspofungin | 29 | 0.03 | 0.06 | |
Aspergillus versicolor | Amphotericin B¶ | 20 | 1 | 2 |
Itraconazole | 20 | 1 | 2 | |
Isavuconazole | 75 | 0.25 | 0.5 | |
Posaconazole | 20 | 0.5 | 1 | |
Voriconazole | 20 | 0.5 | 1 | |
Caspofungin | 20 | 0.03 | 0.12 | |
Aspergillus terreus | Amphotericin B¶ | 22 | 2 | 2 |
Itraconazole | 22 | 0.5 | 0.5 | |
Isavuconazole | 384 | 0.5 | 0.5 | |
Posaconazole | 22 | 0.25 | 0.25 | |
Voriconazole | 22 | 0.25 | 0.5 | |
Caspofungin | 16 | 0.03 | 0.06 | |
Fusarium spp | Amphotericin B¶ | 67 | 8 | 32 |
Itraconazole | 67 | 16 | 32 | |
Isavuconazole | 20 | 16 | >16 | |
Posaconazole | 67 | 16 | 32 | |
Voriconazole | 67 | 16 | 32 | |
Caspofungin | 13 | >8 | >8 | |
Scedosporium apiospermum | Amphotericin B¶ | 26 | 2 | 8 |
Itraconazole | 26 | 1 | 32 | |
Isavuconazole | 16 | 4 | 4 | |
Posaconazole | 26 | 0.25 | 1 | |
Voriconazole | 13 | 0.12 | 0.25 | |
Micafungin | 36 | >16 | >16 | |
Lomentospora prolificans | Amphotericin B¶ | 80 | 16 | 32 |
Itraconazole | 80 | 64 | 64 | |
Isavuconazole | 6 | 16 | - | |
Posaconazole | 80 | 16 | 32 | |
Voriconazole | 55 | 4 | 4 | |
Micafungin | 17 | >32 | >32 | |
Mucorales | Amphotericin B¶ | 86 | 0.25 | 2 |
Itraconazole | 86 | 1 | 32 | |
Isavuconazole | 45 | 2 | 16 | |
Posaconazole | 86 | 0.5 | 4 | |
Voriconazole | 86 | 16 | 128 |
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