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Indications and potential indications for thrombolytic therapy in venous thromboembolism

Indications and potential indications for thrombolytic therapy in venous thromboembolism
Indication
  • High-risk (massive) PE (ie, presence of hypotension related to PE)*
Potential indication
  • Patients with severe right ventricular dysfunction due to PE (ie, intermediate risk PE)
  • Others:
    • Presence of severe hypoxemia (particularly in those with a contribution from concomitant cardiopulmonary disease)
    • Patients with acute PE who appear to be decompensating but are not yet hypotensive
    • Extensive clot burden

PE: pulmonary embolism.

* This indication is widely accepted; the other potential indications require careful review of the risks of thrombolytic therapy and potential benefits.
Graphic 82171 Version 4.0

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