Airflow limitation |
FEV1 <60% predicted (adults or children) or <1.5 L (adults) |
FEV1 <75% predicted (adults or children) for exercise or eucapnic voluntary hyperpnoea challenge |
Spirometry quality |
Inability to perform acceptable and repeatable spirometry maneuvers throughout the test procedure |
Cardiovascular and other problems |
Myocardial infarction or stroke in last three months |
Uncontrolled hypertension |
Known aortic aneurysm |
Recent eye surgery or intracranial pressure elevation risk |
General |
Inability to perform any of the testing maneuvers, such as inhaling the challenge agent consistently or exercising on treadmill or bicycle during an exercise challenge |
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