Key histologic features |
Diffuse distribution |
Uniform temporal appearance |
Alveolar septal thickening due to organizing fibrosis, usually diffuse |
Airspace organization (may be patchy or diffuse) |
Hyaline membranes (may be focal or diffuse) |
Pertinent negative findings |
Lack of granulomas, necrosis, or abscesses |
Lack of infectious agents (no viral inclusions and negative results with special stains for organisms) |
Lack of prominent eosinophils and neutrophils |
Negative cultures |
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