The upper solid line indicates the threshold for genome-wide significance (p<5 × 10–8); loci reaching this threshold are labeled in bold font, and individual SNPs mapping to these loci are shown in red. The lower dashed line indicates the threshold for suggestive association (p<1 × 10–6 and p>5 × 10–8); loci reaching this threshold are labeled in non-bold font.
Reprinted by permission from Macmillan Publishers Ltd: Nature Genetics. Hinks A, Cobb J, Marion MC, et al. Dense genotyping of immune-related disease regions identifies 14 new susceptibility loci for juvenile idiopathic arthritis. Nat Genet 2013; 45:664. Copyright © 2013.
www.nature.com/ng.
