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Bullous pemphigoid

Bullous pemphigoid
This H&E stain of a skin tissue biopsy specimen from an early lesion of bullous pemphigoid demonstrates epidermal spongiosis; eosinophils within the epidermis; and a mixed, perivascular, cellular infiltrate in the upper dermis.
H&E: hematoxylin and eosin.
Reproduced with permission from: Leiferman KM, Peters MS. Eosinophils in cutaneous diseases. In: Fitzpatrick's Dermatology in General Medicine, 8th ed, Goldsmith L, Katz S, Gilchrest B, et al (Eds), McGraw-Hill, New York 2012. Copyright © 2012 McGraw-Hill Companies, Inc.
Graphic 79687 Version 3.0