Symptoms of SDB (eg, excessive daytime sleepiness, disrupted sleep, choking during sleep, snoring, morning headaches) |
Arterial blood gases showing hypoventilation (PaCO2 >45 mmHg [6 kPa]), or daytime hypoxemia |
FVC <50% predicted |
Severely reduced PImax (<60% predicted) |
Unexplained cor pulmonale, elevated serum bicarbonate, or polcythemia |
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