Version October 2024
| Clinical features |
| Dermatologic – Pruritus, flushing, urticaria/angioedema, diaphoresis |
| Eyes – Conjunctival injection, lacrimation, periorbital edema, pruritus |
| Respiratory tract – Nose/oropharynx (sneezing, rhinorrhea, nasal congestion, oral pruritus, metallic taste), upper airway (hoarseness, stridor, sense of choking, laryngeal edema), lower airway (dyspnea, tachypnea, wheezing, cough, cyanosis) |
| Cardiovascular – Conduction disturbances, tachycardia, bradycardia (if severe), arrhythmias, hypotension, cardiac arrest |
| Gastrointestinal – Nausea/vomiting, abdominal cramping, bloating, diarrhea |
| Neurologic – Sense of impending doom, syncope, dizziness, seizures |
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