A diagnostic Reed-Sternberg cell with two nuclei is seen in the center (arrow) with a prominent eosinophilic nucleolus present in each nucleus. There is some chromatin clearing around each nucleolus. Several mononuclear Reed-Sternberg variants are also present in the upper half of the field (dashed arrow).
Reproduced with permission from: Weiss LM, Warnke RA, Hansmann ML, et al. Pathology of Hodgkin Lymphoma. In: Hodgkin Lymphoma, 2nd ed, Hoppe RT, Mauch PT, Armitage JO, et al (Eds), Lippincott Williams & Wilkins, Philadelphia 2007. Copyright © 2007 Lippincott Williams & Wilkins.
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