Risk factor | Prevalence | Grades 3 to 5 toxicity | OR | 95% CI | Score | ||
No. | Percent | No. | Percent | ||||
Age ≥72 years | 270 | 54 | 163 | 60 | 1.85 | 1.22 to 2.82 | 2 |
Cancer type GI or GU | 185 | 37 | 120 | 65 | 2.13 | 1.39 to 3.24 | 2 |
Chemotherapy dosing, standard dose | 380 | 76 | 204 | 54 | 2.13 | 1.29 to 3.52 | 2 |
Number of chemotherapy drugs, polychemotherapy | 351 | 70 | 192 | 55 | 1.69 | 1.08 to 2.65 | 2 |
Hemoglobin <11 g/dL (male), <10 g/dL (female) | 62 | 12 | 46 | 74 | 2.31 | 1.15 to 4.64 | 3 |
Creatinine clearance (Jelliffe, ideal weight) <34 mL/min | 44 | 9 | 34 | 77 | 2.46 | 1.11 to 5.44 | 3 |
Hearing, fair or worse | 123 | 25 | 76 | 62 | 1.67 | 1.04 to 2.69 | 2 |
Number of falls in last six months, one or more | 91 | 18 | 61 | 67 | 2.47 | 1.43 to 4.27 | 3 |
IADL: Taking medications, with some help/unable | 39 | 8 | 28 | 72 | 1.50 | 0.66 to 3.38 | 1 |
MOS: Walking one block, somewhat limited/limited a lot | 109 | 22 | 69 | 63 | 1.71 | 1.02 to 2.86 | 2 |
MOS: Decreased social activity because of physical/emotional health, limited at least sometimes | 218 | 44 | 126 | 58 | 1.36 | 0.90 to 2.06 | 1 |
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