Radiation field definitions* |
Involved-site radiation therapy (ISRT) |
ISRT uses three-dimensional based simulation. The clinical target volume (CTV) encompasses the pre-chemotherapy volume but excludes initially uninvolved, displaced organs after disease regression. Fusion with pre-chemotherapy PET imaging can enhance the CTV definition. Expansion from CTV to internal target volume to planning target volume depends on internal motion and daily setup uncertainties. |
Involved-node radiation therapy (INRT) |
INRT can be regarded as a special case of ISRT wherein upfront PET-CT is acquired with the patient in the treatment position, using the same breathing instructions and immobilization devices that will be used later for RT. |
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