Formation | Assay | Circadian rhythm | LSC | Comments |
OC | S* | Y | 21% | Lack of standardization, rapidly degraded in serum, requires collection on ice |
BSAP | S* | N | 28% | Cross-reactivity with liver isoform (15 to 20%) |
PINP/PICP | S* | Y | 21%/24% | |
Resorption | ||||
NTX | U*,S | Y | 35% (S), 70% (U) | |
CTX | U,S* | Y | 30% (S), 80% (U) | |
D-PYR | U | Y | 26% | |
PYD | U* | Y | 36% | |
HYP | U | Reflects bone resorption and dietary intake | ||
TRACP5b | S | Y | 17% |
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