Severe blood pressure elevation: |
Systolic blood pressure ≥160 mmHg and/or diastolic blood pressure ≥110 mmHg on 2 occasions at least 4 hours apart while the patient is on bedrest; however, antihypertensive therapy generally should be initiated upon confirmation of severe hypertension, in which case criteria for severe blood pressure elevation can be satisfied without waiting until 4 hours have elapsed |
Symptoms of central nervous system dysfunction: |
New-onset cerebral or visual disturbance, such as: - Photopsia, scotomata, cortical blindness, retinal vasospasm
- Severe headache (ie, incapacitating, "the worst headache I've ever had") or headache that persists and progresses despite analgesic therapy with acetaminophen and not accounted for by alternative diagnoses
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Hepatic abnormality: |
- Impaired liver function not accounted for by another diagnosis and characterized by serum transaminase concentration >2 times the upper limit of the normal range
- Severe persistent right upper quadrant or epigastric pain unresponsive to medication and not accounted for by an alternative diagnosis
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Thrombocytopenia: |
- Platelet count <100,000 platelets/microL
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Kidney function impairment: |
- Serum creatinine >1.1 mg/dL [97.2 micromol/L]
- Doubling of the serum creatinine concentration in the absence of other kidney disease
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Pulmonary edema |