The pathways within the endothelial cell that contribute to renal cell carcinoma progression
The pathways within the endothelial cell that contribute to renal cell carcinoma progression
Vascular endothelial growth factor (VEGF) binds to its receptors inducing vascular growth. Several agents block VEGF either by binding to it (antibodies), blocking receptor signaling (small molecules), or by blocking at several steps inside the endothelial cell.