Version October 2024
| General indications |
| PaO2 ≤55 mmHg (7.32 kPa) or SaO2 ≤88 percent |
| In the presence of cor pulmonale |
| PaO2 ≤59 mmHg (7.85 kPa) or SaO2 ≤89 percent |
| EKG evidence of P pulmonale |
| Hematocrit >55 percent |
| Clinical evidence of right heart failure |
| Specific situations |
| PaO2 ≥60 mmHg (7.98 kPa) or SaO2 ≥90 percent with lung disease and other clinical needs such as sleep apnea with nocturnal desaturation not corrected by CPAP. |
| If the patient meets criteria at rest, O2 should also be prescribed during sleep and exercise, and appropriately titrated. |
| If the patient is normoxemic at rest but desaturates during exercise (PaO2 ≤55 mmHg [7.32 kPa]), O2 is generally prescribed for use during exercise. For patients who desaturate (PaO2 ≤55 mmHg [7.32 kPa]) during sleep, further evaluation with polysomnography may be indicated to assess for sleep-disordered breathing. |
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