Nature of operation | Common pathogens | Recommended antimicrobials | Usual adult dose* | Redose interval¶ |
Cardiac procedures: coronary artery bypass, cardiac device insertion procedures (eg, pacemaker implantation), placement of ventricular assist devices | Staphylococcus aureus, Staphylococcus epidermidis | CefazolinΔ | <120 kg: 2 g IV ≥120 kg: 3 g IV | 4 hours |
OR cefuroxime | 1.5 g IV | 4 hours◊ | ||
OR vancomycin§ | 15 mg/kg IV (max 2 g) | N/A | ||
OR clindamycin | 900 mg IV | 6 hours |
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