Diseases unrelated to travel can appear after exotic travel |
Infections can be acquired en route or on brief layovers |
Fever related to travel exposures usually begins during travel or shortly after return, but can rarely be delayed for months or years |
Defining the range of relevant incubation periods can help limit the differential diagnosis |
Malaria is still possible even if an initial malaria smear is negative |
Patients with acute falciparum malaria may have a normal physical examination and no fever when first seen |
Early symptoms of self-limited infections and life-threatening infections may be indistinguishable |
Risks for infectious diseases and manifestations of infections in local residents and in visitors to a geographic region may differ widely |
Risks for infectious diseases vary from one area to another and may vary depending upon the season and year |
Familiar infectious diseases acquired during travel may have an unusual resistance pattern or may be acquired during an unexpected time of year (eg, influenza in July) |
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