Condition | Glucose | Insulin | Glucagon | Epinephrine | Autonomic symptom response |
No diabetes | ↓ | Decreases | Increases | Increases | Activated |
T1DM | ↓ | No decrease* | No increase* | Attenuated increase*¶ | Attenuated activation or absent¶ |
T2DM | |||||
Early | ↓ | Decreases | Increases | Increases | Activated |
Late (absolute endogenous insulin deficiency) | ↓ | No decrease* | No increase* | Attenuated increase*¶ | Attenuated activation or absent¶ |
* Defective glucose counterregulation.
¶ Hypoglycemia unawareness.Do you want to add Medilib to your home screen?