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Alterations in the somatotropic axis in HIV infection

Alterations in the somatotropic axis in HIV infection
  HIV-infected, no wasting or lipodystrophy HIV-infected, lipodystrophy AIDS wasting
GH Normal ↓ ↑
IGF-1 Normal Normal ↓
IGF-BP-3 Normal Normal Normal or ↓
GH: growth hormone; IGF-1: insulin-like growth factor-1; IGF-BP-3: insulin-like growth factor-binding protein-3.
Graphic 75394 Version 2.0