Regimen | Dosage and schedule | Frequency |
ABVD[1] | ||
Doxorubicin | 25 mg/m2 IV on days 1 and 15 | Repeat cycle every 28 days |
Bleomycin | 10 units*/m2 IV on days 1 and 15 | |
Vinblastine | 6 mg/m2 IV on days 1 and 15 | |
Dacarbazine | 375 mg/m2 IV on days 1 and 15 | |
BV+AVD[2] | ||
Brentuximab vedotin | 1.2 mg/kg IV on days 1 and 15 | Repeat cycle every 28 days |
Doxorubicin | 25 mg/m2 IV on days 1 and 15 | |
Vinblastine | 6 mg/m2 IV on days 1 and 15 | |
Dacarbazine | 375 mg/m2 IV on days 1 and 15 | |
Escalated BEACOPP[3,4] | ||
Bleomycin | 10 units*/m2 IV on day 8 | Repeat cycle every 21 days |
Etoposide | 200 mg/m2 IV on days 1 through 3¶ | |
Doxorubicin | 35 mg/m2 IV on day 1¶ | |
CyclophosphamideΔ | 1250 mg/m2 IV on day 1¶ | |
Vincristine | 1.4 mg/m2 (maximum 2 mg) IV on day 8 | |
Procarbazine | 100 mg/m2 oral on days 1 through 7 | |
Prednisone | 40 mg/m2 oral on days 1 through 14 | |
G-CSF | SQ starting on day 8 |
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