Nonmalignant hematologic conditions |
Acute blood loss |
Acute hemolytic anemia |
Iron deficiency anemia |
Treatment of vitamin B12 deficiency |
Rebound effect after treatment of immune thrombocytopenia (ITP) |
Rebound effect after ethanol-induced thrombocytopenia |
Malignant conditions |
Metastatic cancer |
Lymphoma |
Rebound effect following use of myelosuppressive agents |
Acute and chronic inflammatory conditions |
Rheumatologic disorders, vasculitides |
Inflammatory bowel disease |
Celiac disease |
Kawasaki disease |
Nephrotic syndrome |
POEMS syndrome (osteosclerotic myeloma) |
Tissue damage |
Thermal burns |
Myocardial infarction |
Severe trauma |
Acute pancreatitis |
Post-surgical period, especially post-splenectomy |
Infections |
Chronic infections |
Tuberculosis |
Acute bacterial and viral infections |
Exercise |
Allergic reactions |
Functional and surgical asplenia |
Reaction to medications |
Vincristine |
Epinephrine, glucocorticoids |
Interleukin-1B |
All-trans retinoic acid |
Thrombopoietin, thrombopoietin receptor agonists |
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