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Virilization (cross-sectional view)

Virilization (cross-sectional view)
Typical and atypical differentiation of the urogenital sinus and external genitalia. Diagrams of typical female and male anatomy flank a series of schematic representations of different degrees of virilization of individuals with an XX karyotype, graded using the scale developed by Prader for XX patients with CAH. Because antimüllerian hormone is not produced in high amounts in XX infants with CAH, the uterus persists even when the external genitalia have a typical male appearance (Prader V).
CAH: congenital adrenal hyperplasia.
Reproduced with permission from: White PC, Speiser PW. Congenital adrenal hyperplasia due to 21-hydroxylase deficiency. Endocr Rev 2000; 21:245. http://edrv.endojournals.org/. Copyright © 2000 The Endocrine Society.
Graphic 73502 Version 12.0