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Histologic features of respiratory bronchiolitis pattern

Histologic features of respiratory bronchiolitis pattern
Key histologic features
Bronchiolocentric alveolar macrophage accumulation
Mild bronchiolar fibrosis and chronic inflammation
Macrophages have dusty brown cytoplasm (may be positive for iron stains)
Pertinent negative findings
Lack of diffuse macrophage accumulation
Lack of interstitial fibrosis and/or honeycomb fibrosis
Absence of fibroblast foci
Graphic 73463 Version 3.0

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