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Causes of secondary hyperparathyroidism

Causes of secondary hyperparathyroidism
Chronic kidney disease
  • Impaired calcitriol production
  • Hyperphosphatemia
  • Hypocalcemia
Decreased calcium intake
Calcium malabsorption
  • Vitamin D deficiency
  • Bariatric surgery
  • Celiac disease
  • Pancreatic disease (fat malabsorption)
Renal calcium loss
  • Idiopathic hypercalciuria
  • Loop diuretics
Inhibition of bone resorption
  • Bisphosphonates
  • Denosumab
Hungry bone syndrome
Adapted from: Prince RL. Secondary and tertiary hyperparathyroidism. In: Primer on the metabolic bone diseases and disorders of mineral metabolism, 6th, Favus MJ (Ed), ASBMR, 2006. p. 191.
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