Type of infection | Drug | Adult dose |
Localized cutaneous infection | ||
Preferred | Penicillin V | 500 mg every 6 hours orally |
Amoxicillin | 500 mg every 8 hours orally | |
Alternatives | Cephalexin | 500 mg every 6 hours orally |
Ciprofloxacin* | 250 mg every 12 hours orally | |
Clindamycin | 300 mg every 8 hours orally | |
Erythromycin¶ | 500 mg every 6 hours orally | |
Diffuse cutaneous infection OR systemic infection (bacteremia) | ||
Preferred | Penicillin G | 2 to 4 million units every 4 hours IV |
Alternatives | Ceftriaxone | 2 g every 24 hours IV |
Cefazolin | 1 g every 8 hours IV | |
Imipenem | 500 mg every 6 hours IV | |
CiprofloxacinΔ | 400 mg every 12 hours IV | |
Daptomycin | 6 mg/kg every 24 hours IV |
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