Effect of a single dose of the long-acting beta agonist salmeterol versus placebo in exercise induced bronchoconstriction. Salmeterol, but not placebo, protected against a decline in FEV1 with exercise. This effect was seen at both one (left panel) and nine (right panel) hours.
EIB: exercise induced bronchoconstriction; FEV1: forced expiratory volume in one second.
Redrawn from Green CP, Price JF, Arch Dis Child 1992; 67:1014.