Reaction to sting | Result of skin test or venom-specific IgE test | Venom immunotherapy indicated? |
Non-life-threatening, widespread, cutaneous reaction: Generalized urticaria, angioedema, erythema, pruritus | Positive | No*¶ |
Systemic, life-threatening reaction: Possible cutaneous symptoms but also respiratory symptoms (laryngeal edema or bronchospasm) or cardiovascular symptoms (hypotension, shock) | Positive | Yes |
Systemic reaction | Negative | NoΔ |
Large local reaction (>4 inches or 10 cm in diameter, >24-hour duration) | Positive or negative | No* |
Normal reaction (≤4 inches or 10 cm in diameter, <24-hour duration) | Positive or negative | No |
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