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Flame cell in multiple myeloma

Flame cell in multiple myeloma
High power view of a bone marrow aspirate from a patient with multiple myeloma of the IgA type. Multiple abnormal plasma cells can be seen in this view, including a binucleate form (small arrows). The large cell on the right has an abnormal nucleus and a cytoplasm with a reddish (flame-like) tint, due to the presence of IgA protein (arrow).
Courtesy of David S Rosenthal, MD and William C Moloney, MD.
Graphic 72153 Version 2.0

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