Drug-induced pleural fluid eosinophilia

Frequent	Infrequent	Rare
Warfarin^* Propylthiouracil Sulfasalazine	Acebutolol Clozapine Isotretinoin Mesalamine Nitrofurantoin^* Simvastatin Trimipramine	Acyclovir Bromocriptine Crack cocaine Dantrolene^* Fluoxetine^* Gliclazide^* Imidapril Infliximab Tizanidine Valproic acid^* Vitamins B5/H Olanazapine Carbimazole Palenperidone palmitate Kampo (herbal) L-tryptophan

Frequent: 20 to 100 cases reported.

Infrequent: up to 10 cases reported.

Rare: single case report.

Fenfluramine, dexfenfluramine, and practolol have been associated with pleural fluid eosinophilia but have been removed from the market.

* Drugs associated with combined pleural fluid and peripheral blood eosinophilia.

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