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Modified Spigelman score and classification of duodenal polyposis

Modified Spigelman score and classification of duodenal polyposis
Factor Score
1 point 2 points 3 points
Number of polyps 1 to 4 5 to 20 >20
Polyp size (mm) 1 to 4 5 to 10 >10
Histology Tubular Tubulovillous Villous
Dysplasia Low grade -- High grade
Classification: no polyp: stage 0; 1 to 4 points: stage I; 5 to 6 points: stage II; 7 to 8 points: stage III; 9 to 12 points: stage IV.
Reproduced with permission from: Saurin J, Gutknecht C, Napoleon B, et al. Surveillance of duodenal adenomas in familial adenomatous polyposis reveals high cumulative risk of advanced disease. J Clin Oncol 2004; 22:493. Copyright © 2004 American Society of Clinical Oncology (ASCO).
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