This figure illustrates the 3 types of TRAb present in autoimmune thyroid disease: stimulating, blocking, and neutral.
TRAb: thyrotropin receptor antibody.
Adapted from: Latif R, Morshed SA, Zaidi M, Davies TF. The thyroid-stimulating hormone receptor: impact of thyroid-stimulating hormone and thyroid-stimulating hormone receptor antibodies on multimerization, cleavage, and signaling. Endocrinol Metab Clin North Am. 2009; 38:319.