(HBeAg-positive) | (HBeAg-negative) | |||
Entecavir 0.5 mg (n = 314)* | Lamivudine 100 mg (n = 314)* | Entecavir 0.5 mg (n = 296)* | Lamivudine 100 mg (n = 287)* | |
Histologic improvement (Knodell scores) | ||||
Improvement¶ | 72%Δ | 62% | 70%Δ | 61% |
No improvement | 21% | 24% | 19% | 26% |
Ishak Fibrosis Score | ||||
Improvement◊ | 39% | 35% | 36% | 38% |
No change | 46% | 40% | 41% | 34% |
Worsening◊ | 8% | 10% | 12% | 15% |
Missing week 48 biopsy | 7% | 14% | 10% | 13% |
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